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DENVER –The year’s first human cases of West Nile virus in Colorado were confirmed Thursday, the Colorado Department of Public Health and Environment reported.

The two infected people were found in Saguache and Pueblo counties, officials said.

State health officials advised all Colorado residents to take precautions against West Nile virus by wearing insect repellent and using other methods to avoid mosquito bites this holiday weekend.

Last year, Colorado reported 322 cases of West Nile virus disease, including seven deaths.

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“Although we can’t predict how much West Nile virus activity will occur this summer, we know that the risk for human disease exists and people should take measures to protect themselves,” state public health veterinarian Jennifer House said.

To help prevent West Nile virus infection, follow the four D’s:

  • DRAIN standing water around your house weekly. Don’t forget to drain water from tires, cans, flowerpots, clogged rain gutters, rain barrels, toys and puddles.
  • DUSK and DAWN are when mosquitoes that carry the virus are most active. Limit outdoor activities or take precautions to prevent mosquito bites during these times.
  • DEET is an effective ingredient to look for in insect repellents. Always follow label instructions carefully.
  • DRESS in long sleeves and pants in areas where mosquitoes are active.

For more information about West Nile virus, visit www.FightTheBiteColorado.com.